
Heparinoids are mucopolysaccharides obteined from different animal organs, especially from duodenum, through soft extraction processes which guarantee the integrity of the active elements.
Heparinoids are heteropolysaccharides of straight chains with different degree of sulphation. The principal constituents, Dermatan Sulfate A, Heparan Sulfate, and Chondroitin Sulphate, present a wide spectrum of biological activities, although very low anticoagulant capacity.
| | CAS NO. 54328-33-5 |  |

Heparinoids have the same properties of each one of its individual constituents
with a pronounced synergism, which increases the pharmacological effect of the
individual components.
At therapeutic level it can be determined:
- Activation of the lipoprotein elimination by stimulation
of the lipases responsible for their degradation ( lipasemic activity ).
- Inhibition of cell proliferation in the vascular walls.
- Regulation of the transport of plasmatic proteins through
the capilary wall, in this way, preventing from protein losses at level of
kidney glomerulus structures.
Heparinoids prevent from lipoprotein and chylomicrons depositionin in the vascular
wall;
Therefore, cholesterol accumulation in arterial tissues is inhibited, which contributes
to decrease artherosclerosis disorders.

In cosmetics and dermopharmaceutical the applications are as follows:
- Acting on epidermis as antiedematous and anticongestive agents,
favouring the elimination of superficial minor bleeding since heparinoids
fluidize blood accumulated in the arterioles and accelerate the reabsorption
of haematomas.
- Moisturizing effect mainly due to its content of Chondroitin
Sulfate and Dermatan Sulfate.
- Anticellulitic and antivaricose properties acting, therefore,
against flaccidity and inflamation of altered epidermal areas.

The composition and the purity of the product can be personalized as request. In this sense two estimated specifications are included. These specifications can be regulated depending on the needs.
Organoleptic Characteristics |
|
Appearance |
Higroscopic fine powder |
Color |
White or beige |
|
Chemical parameters |
Grades |
|
|
Desiccation loss (1% H2O) |
|
PH (1% H2O) |
|
Nitrogen or .d.b. (Kjeldahl) |
|
Specific rotation |
|
Sulfur |
|
Heavy metals |
|
Electrophoresis |
Characteristic |
Characteristic |
|
Biological activity |
|
|
Microbiological parameters |
Total count of aerobics |
|
Pathogen |
Absence /10g |
Absence /10g |
|
|

Heparinoids are available in bulk amounts. It is presented in solid powder form. The composition
and purity of the product can be customized upon request. In this sense we include
two orientative specifications which can be modified depending on individual
needs.
|
|